Styryl dyes and genetically encoded pH-sensitive fluorescent proteins like pHluorin are well-established tools for the optical analysis of synaptic vesicle (SV) recycling at presynaptic boutons.Here, we describe the development of a new class of fluorescent probes based on pH-sensitive organic dyes covalently bound to lipids, providing a promising
Electronic annotation of scientific data is very similar to annotation of documents.Both types of annotation amplify the original object, add related knowledge to it, and dispute or support assertions in it.In each case, annotation is a framework for discourse about the Wooden Base original object, and, in each case, an annotation needs to clearly
Most of the Helicobacter pylori infections occur in developing countries.The risk factors for H.pylori infections are poverty, overcrowding, and unhygienic conditions, which are common problems in under-privileged countries such as Nepal.Despite having a high risk of H.pylori infections, no national level study has been conducted to assess prevalen
Abstract Among the three major food crops (rice, wheat and maize), wheat is unique in accumulating gluten proteins in its grains.Of these proteins, the high and low molecular weight glutenin subunits (HMW-GSs and LMW-GSs) form glutenin macropolymers that are vital for the diverse end-uses of wheat grains.In this work, we developed a new series of F
Rhodopseudomonas palustris CGA009 is a metabolically robust microbe that can utilize lignin breakdown products to produce polyhydroxyalkanoates (PHAs), biopolymers with the potential to replace conventional plastics.Our recent efforts suggest PHA granule formation is a limiting factor for maximum production of the bioplastic poly(3-hydroxybutyrate-